Researchers warn – keep the AstraZeneca vaccination three months apart

Published on 05/28/2021

The European Medicines Agency (EMA) now recommends Biontech’s corona vaccine for adolescents aged 12 to 15 as well. This means that children in this age group can also receive a vaccination offer.

Several medical professionals warn against shortening the interval between two vaccinations with the AstraZeneca vaccine.

This could increase the risk of thrombosis. It is safer to keep the interval of three months to the second vaccination.

D.he Greifswald medical professor Andreas Greinacher warns against “ Zeit Online ” against shortening the vaccination interval for the AstraZeneca vaccine from twelve to four weeks. 

He fears that a shorter interval between the two vaccine doses could increase the risk of rare side effects . 

What is meant are blood clots that mainly affect the sinus veins of the brain and the large abdominal veins and are associated with platelet deficiency and bleeding.

“I can only recommend everyone to wait three months for the AstraZeneca vaccination,” said Greinacher. 

The blood clotting expert described a possible mechanism of the rare side effects.

The focus is on certain antibodies that can be detected in the blood of those affected and are said to be responsible for activating coagulation.

In some people who have been vaccinated, these antibodies can be found in the blood after vaccination without any side effects.

After three months, Greinacher reports, the antibodies have probably disappeared from the bloodstream again.

If, however, the vaccine is re-vaccinated after four instead of twelve weeks, that is problematic.

“There will be the situation that people who have formed antibodies unnoticed after the first vaccination will be vaccinated a second time while there are still many antibodies in their bloodstream.”

Greinacher believes that this constellation increases the risk of the rare side effects.

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So far no data are available for Greinacher’s hypothesis. Some experts such as the hematology professor and platelet expert Pål André Holme from the University Hospital Oslo say that Greinacher could theoretically be right, but point out that his considerations have so far been “pure speculation”. 

Others like Michael Nagler, senior physician in clinical chemistry at Inselspital in Bern, consider Greinacher’s considerations plausible.

As a precaution, Nagler also advises against shortening the vaccination interval.

The shortening of the vaccination interval was only made possible in May by the federal and state governments, although the Standing Vaccination Commission (Stiko) continues to recommend a vaccination interval of twelve weeks. 

The effectiveness is probably significantly higher with the longer distance.

A 44-year-old radio presenter for the BBC died in Great Britain this week as a result of a brain thrombosis following the AstraZeneca vaccination. 

A warning signal is severe headache that occurs about a week after the vaccination and is different from headaches that are otherwise felt with migraines or tension.

Source: WORLD

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